DNA sequencing in practice

An important part of the Digital DNA project is to understand practices around working with DNA and related technologies. Therefore, in March 2024, the whole research team went to Nesbru high school to sequence DNA. A sequencing kit was purchased online. At the high school we had expert help from Priscila, a biology teacher who previously worked with DNA forensics in Brazil and Norway, and Dyre, a biology teacher who had worked in a company developing sequencing technology. We were also joined by a group of biology students from the International Baccalaureate program at Nesbru, which also gave us the opportunity for exchange and common learning experiences. 

a photo of the team

Photo: Mareile Kaufmann

This was an informative and social field trip that gave us a lot of input into the Digital DNA project. We especially appreciated the first-hand experience of how sensitive a process and its technologies can be. Even the smallest inconsistency or error can confound the result. The process of sequencing also consists of many steps and a lot of preparations, which, luckily for us, Priscila had prepared for us. We took part in the last step of the process where we piped liquid with different people’s DNA into gel to then see who matched the DNA sample found at the fictious crime scene. 

Team members testing DNA sequencing
Photo: Mareile Kaufmann

We ended the trip by having pizza with the teachers and students, where we also presented the Digital DNA project and all our subprojects. In doing so, we introduced them to a social science angle to their biological practices and knowledges, a perspective that teachers and students considered new and important. Some of the topics we talked about were police’s handling of DNA evidence, the social implications of new DNA processing methods, DNA storage, commercial direct-to-consumer genomics and molecular computing. 

Published Nov. 12, 2024 9:50 AM - Last modified Feb. 12, 2026 11:10 AM